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  1. Research Article

    Combined GWAS and ‘guilt by association’-based prioritization analysis identifies functional candidate genes for body size in sheep

    Body size in sheep is an important indicator of productivity, growth and health as well as of environmental adaptation. It is a composite quantitative trait that has been studied with high-throughput genomic m...

    Antonios Kominakis, Ariadne L. Hager-Theodorides, Evangelos Zoidis, Aggeliki Saridaki, George Antonakos and George Tsiamis

    Genetics Selection Evolution 2017 49:41

    Published on: 28 April 2017

  2. Short communication

    Genomic prediction from observed and imputed high-density ovine genotypes

    Genomic prediction using high-density (HD) marker genotypes is expected to lead to higher prediction accuracy, particularly for more heterogeneous multi-breed and crossbred populations such as those in sheep ...

    Nasir Moghaddar, Andrew A. Swan and Julius H. J. van der Werf

    Genetics Selection Evolution 2017 49:40

    Published on: 20 April 2017

  3. Research Article

    Detection of QTL for traits related to adaptation to sub-optimal climatic conditions in chickens

    Growth traits can be used as indicators of adaptation to sub-optimal conditions. The current study aimed at identifying quantitative trait loci (QTL) that control performance under variable temperature conditi...

    Ching-Yi Lien, Michèle Tixier-Boichard, Shih-Wen Wu, Woei-Fuh Wang, Chen Siang Ng and Chih-Feng Chen

    Genetics Selection Evolution 2017 49:39

    Published on: 20 April 2017

  4. Research Article

    Deciphering mechanisms underlying the genetic variation of general production and liver quality traits in the overfed mule duck by pQTL analyses

    The aim of this study was to analyse the mechanisms that underlie phenotypic quantitative trait loci (QTL) in overfed mule ducks by identifying co-localized proteomic QTL (pQTL). The QTL design consisted of th...

    Yoannah François, Alain Vignal, Caroline Molette, Nathalie Marty-Gasset, Stéphane Davail, Laurence Liaubet and Christel Marie-Etancelin

    Genetics Selection Evolution 2017 49:38

    Published on: 19 April 2017

  5. Research Article

    Use of multi-trait and random regression models to identify genetic variation in tolerance to porcine reproductive and respiratory syndrome virus

    A host can adopt two response strategies to infection: resistance (reduce pathogen load) and tolerance (minimize impact of infection on performance). Both strategies may be under genetic control and could thus...

    Graham Lough, Hamed Rashidi, Ilias Kyriazakis, Jack C. M. Dekkers, Andrew Hess, Melanie Hess, Nader Deeb, Antti Kause, Joan K. Lunney, Raymond R. R. Rowland, Han A. Mulder and Andrea Doeschl-Wilson

    Genetics Selection Evolution 2017 49:37

    Published on: 19 April 2017

  6. Research article

    Genome-wide association study and accuracy of genomic prediction for teat number in Duroc pigs using genotyping-by-sequencing

    The number of teats in pigs is related to a sow’s ability to rear piglets to weaning age. Several studies have identified genes and genomic regions that affect teat number in swine but few common results were ...

    Cheng Tan, Zhenfang Wu, Jiangli Ren, Zhuolin Huang, Dewu Liu, Xiaoyan He, Dzianis Prakapenka, Ran Zhang, Ning Li, Yang Da and Xiaoxiang Hu

    Genetics Selection Evolution 2017 49:35

    Published on: 29 March 2017

  7. Research Article

    Metafounders are related to F st fixation indices and reduce bias in single-step genomic evaluations

    Metafounders are pseudo-individuals that encapsulate genetic heterozygosity and relationships within and across base pedigree populations, i.e. ancestral populations. This work addresses the estimation and us...

    Carolina A. Garcia-Baccino, Andres Legarra, Ole F. Christensen, Ignacy Misztal, Ivan Pocrnic, Zulma G. Vitezica and Rodolfo J. C. Cantet

    Genetics Selection Evolution 2017 49:34

    Published on: 10 March 2017

  8. Research Article

    Selecting sequence variants to improve genomic predictions for dairy cattle

    Millions of genetic variants have been identified by population-scale sequencing projects, but subsets of these variants are needed for routine genomic predictions or genotyping arrays. Methods for selecting s...

    Paul M. VanRaden, Melvin E. Tooker, Jeffrey R. O’Connell, John B. Cole and Derek M. Bickhart

    Genetics Selection Evolution 2017 49:32

    Published on: 7 March 2017

  9. Research Article

    Estimation of breeding values for uniformity of growth in Atlantic salmon (Salmo salar) using pedigree relationships or single-step genomic evaluation

    In farmed Atlantic salmon, heritability for uniformity of body weight is low, indicating that the accuracy of estimated breeding values (EBV) may be low. The use of genomic information could be one way to incr...

    Panya Sae-Lim, Antti Kause, Marie Lillehammer and Han A. Mulder

    Genetics Selection Evolution 2017 49:33

    Published on: 7 March 2017

  10. Research Article

    A hybrid method for the imputation of genomic data in livestock populations

    This paper describes a combined heuristic and hidden Markov model (HMM) method to accurately impute missing genotypes in livestock datasets. Genomic selection in breeding programs requires high-density genotyp...

    Roberto Antolín, Carl Nettelblad, Gregor Gorjanc, Daniel Money and John M. Hickey

    Genetics Selection Evolution 2017 49:30

    Published on: 3 March 2017

  11. Research Article

    Estimating the genetic merit of sires by using pooled DNA from progeny of undetermined pedigree

    DNA-based predictions for hard-to-measure production traits hold great promise for selective breeding programs. DNA pooling might provide a cheap genomic approach to use phenotype data from commercial flocks w...

    Amy M. Bell, John M. Henshall, Laercio R. Porto-Neto, Sonja Dominik, Russell McCulloch, James Kijas and Sigrid A. Lehnert

    Genetics Selection Evolution 2017 49:28

    Published on: 28 February 2017

  12. Research Article

    TCF21 is related to testis growth and development in broiler chickens

    Large amounts of fat deposition often lead to loss of reproductive efficiency in humans and animals. We used broiler chickens as a model species to conduct a two-directional selection for and against abdominal...

    Hui Zhang, Wei Na, Hong-Li Zhang, Ning Wang, Zhi-Qiang Du, Shou-Zhi Wang, Zhi-Peng Wang, Zhiwu Zhang and Hui Li

    Genetics Selection Evolution 2017 49:25

    Published on: 24 February 2017

  13. Research Article

    Evaluation of the accuracy of imputed sequence variant genotypes and their utility for causal variant detection in cattle

    The availability of dense genotypes and whole-genome sequence variants from various sources offers the opportunity to compile large datasets consisting of tens of thousands of individuals with genotypes at mil...

    Hubert Pausch, Iona M. MacLeod, Ruedi Fries, Reiner Emmerling, Phil J. Bowman, Hans D. Daetwyler and Michael E. Goddard

    Genetics Selection Evolution 2017 49:24

    Published on: 21 February 2017

  14. Research article

    Genetic parameters of resistance to Vibrio aestuarianus, and OsHV-1 infections in the Pacific oyster, Crassostrea gigas, at three different life stages

    In France, two main diseases threaten Pacific oyster production. Since 2008, Crassostrea gigas spat have suffered massive losses due to the ostreid herpesvirus OsHV-1, and since 2012, significant mortalities in c...

    Patrick Azéma, Jean-Baptiste Lamy, Pierre Boudry, Tristan Renault, Marie-Agnès Travers and Lionel Dégremont

    Genetics Selection Evolution 2017 49:23

    Published on: 15 February 2017

  15. Research Article

    Rapid evolution of genetic and phenotypic divergence in Atlantic salmon following the colonisation of two new branches of a watercourse

    Selection acts strongly on individuals that colonise a habitat and have phenotypic traits that deviate from the local optima. Our objective was to investigate the evolutionary rates in Atlantic salmon (Salmo sal...

    Arne Johan Jensen, Lars Petter Hansen, Bjørn Ove Johnsen and Sten Karlsson

    Genetics Selection Evolution 2017 49:22

    Published on: 14 February 2017

  16. Research Article

    Genome-wide detection of genetic markers associated with growth and fatness in four pig populations using four approaches

    Genome-wide association studies (GWAS) have been extensively used to identify genomic regions associated with a variety of phenotypic traits in pigs. Until now, most GWAS have explored single-trait association...

    Yuanmei Guo, Yixuan Huang, Lijuan Hou, Junwu Ma, Congying Chen, Huashui Ai, Lusheng Huang and Jun Ren

    Genetics Selection Evolution 2017 49:21

    Published on: 14 February 2017

  17. Research Article

    Genome-wide association mapping for milk fat composition and fine mapping of a QTL for de novo synthesis of milk fatty acids on bovine chromosome 13

    Bovine milk is widely regarded as a nutritious food source for humans, although the effects of individual fatty acids on human health is a subject of debate. Based on the assumption that genomic selection offe...

    Hanne Gro Olsen, Tim Martin Knutsen, Achim Kohler, Morten Svendsen, Lars Gidskehaug, Harald Grove, Torfinn Nome, Marte Sodeland, Kristil Kindem Sundsaasen, Matthew Peter Kent, Harald Martens and Sigbjørn Lien

    Genetics Selection Evolution 2017 49:20

    Published on: 13 February 2017

  18. Research Article

    A genome-wide association study in a large F2-cross of laying hens reveals novel genomic regions associated with feather pecking and aggressive pecking behavior

    Feather pecking and aggressive pecking in laying hens are serious economic and welfare issues. In spite of extensive research on feather pecking during the last decades, the motivation for this behavior is sti...

    Vanessa Lutz, Patrick Stratz, Siegfried Preuß, Jens Tetens, Michael A. Grashorn, Werner Bessei and Jörn Bennewitz

    Genetics Selection Evolution 2017 49:18

    Published on: 3 February 2017

  19. Research Article

    A predictive assessment of genetic correlations between traits in chickens using markers

    Genomic selection has been successfully implemented in plant and animal breeding programs to shorten generation intervals and accelerate genetic progress per unit of time. In practice, genomic selection can be...

    Mehdi Momen, Ahmad Ayatollahi Mehrgardi, Ayoub Sheikhy, Ali Esmailizadeh, Masood Asadi Fozi, Andreas Kranis, Bruno D. Valente, Guilherme J. M. Rosa and Daniel Gianola

    Genetics Selection Evolution 2017 49:16

    Published on: 1 February 2017

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