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Table 2 Top 10 enriched pathways for the three axes

From: On the performance of tests for the detection of signatures of selection: a case study with the Spanish autochthonous beef cattle populations

Pathway

Ngenesa

Totalb

First axis

 Focal adhesion

48

185

 Integrated pancreatic cancer pathway

46

181

 MAPK signalling pathway

43

163

 Lymphocite TarBase

96

533

 Epithelium TarBase

69

340

 TSH signalling pathway

25

70

 Adipogenesis

36

130

 Cytoplasmic ribosomal proteins

27

88

 Muscle cell TarBase

77

424

 GPCRs, class A rhodopsin-like

53

259

Second axis

 Epithelium TarBase

51

340

 Lymphocyte TarBase

62

533

 Translation factors

15

51

 Focal adhesion

27

185

 Adipogenesis

21

130

 Muscle cell TarBase

44

424

 Notch signalling pathway

11

45

 Integrated pancreatic cancer pathway

23

181

 G1 to S cell cycle control

14

77

 Eukaryotic transcription initiation

10

41

Third axis

 Lymphocyte TarBase

304

533

 MAPK signalling pathway

124

165

 Insulin signalling

123

163

 Muscle cell TarBase

240

424

 Calcium regulation in the cardiac cell

116

151

 Focal adhesion

132

185

 Integrated pancreatic cancer pathway

130

181

 Myometrial relaxation and contraction pathways

116

162

 Adipogenesis

99

130

 Epithelium TarBase

191

340

  1. aNgenes: number of genes present in the genomic regions
  2. bTotal: number genes in the pathway