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Fig. 4 | Genetics Selection Evolution

Fig. 4

From: Estimated allele substitution effects underlying genomic evaluation models depend on the scaling of allele counts

Fig. 4

Correlation (a), mean ratio (b), and regression coefficient (c) between allele substitution effects based on unscaled (RRc) and scaled (RRcs) allele counts per minor allele frequency (MAF). For all SNPs with the same MAF the correlation between allele substitution effects (ASE) from RRc and RRcs are plotted in a. The red dashed line in a is a smoothed LOESS. The mean of the ratios between ASE from RRc and RRcs (ASERRcs/ASERRc) for SNPs with the same MAF are plotted in b. The red dashed line in b indicates the ratio between ASE based on RRc and RRcs using the derived equation for uniformly distributed MAF, given the MAF of the SNPs in the real data. For all SNPs with the same MAF, the regression coefficient for the regression of ASE from RRcs on ASE from RRc are plotted in c

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Genetics Selection Evolution

ISSN: 1297-9686