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Table 2 Estimates (± SD) of genetic (\({\sigma}_{a}^{2}\)), batch (\({{{\sigma}}}_{{{b}}{{a}}{{t}}{{c}}{{h}}}^{2}\)) and residual (\({{{\sigma}}}_{{{e}}}^{2}\)) variance components, heritability (\({{{h}}}^{2}\)), and batch incidence (\({{{h}}}_{{{b}}{{a}}{{t}}{{c}}{{h}}}\)) for blood metabolites

From: Integrating on-farm and genomic information improves the predictive ability of milk infrared prediction of blood indicators of metabolic disorders in dairy cows

Traits

\({\upsigma }_{\mathrm{a}}^{2}\)

\({\upsigma }_{\mathrm{batch}}^{2}\)

\({\upsigma }_{\mathrm{e}}^{2}\)

\({h}^{2}\)

\({h}_{\mathrm{batch}}\)

Energy-related metabolites

 Glucose, mmol/L

0.018 ± 0.009

0.040 ± 0.035

0.032 ± 0.007

0.360 ± 0.083

0.444 ± 0.097

 BHBA, mmol/L

0.002 ± 0.002

0.003 ± 0.003

0.014 ± 0.002

0.125 ± 0.049

0.158 ± 0.051

 Urea, mmol/L

0.097 ± 0.061

0.305 ± 0.221

0.443 ± 0.061

0.180 ± 0.068

0.361 ± 0.091

Liver function/hepatic damage

 AST, U/L

136.228 ± 39.725

46.593 ± 18.297

241.761 ± 30.869

0.360 ± 0.091

0.110 ± 0.060

 GGT, U/L

17.049 ± 4.153

0.528 ± 0.288

22.922 ± 3.945

0.427 ± 0.073

0.013 ± 0.013

 PON, U/mL

197.144 ± 34.858

26.971 ± 13.834

129.064 ± 25.22

0.604 ± 0.086

0.076 ± 0.035

Oxidative stress metabolites

 ROMt, mgH2O2/100 mL

0.972 ± 0.485

0.677 ± 0.268

6.481 ± 0.915

0.130 ± 0.065

0.083 ± 0.040

 AOPP, µmol/L

5.374 ± 2.769

19.491 ± 8.748

54.696 ± 3.459

0.089 ± 0.045

0.245 ± 0.073

 FRAP, µmol/L

45.411 ± 4.575

295.345 ± 114.219

867.563 ± 155.12

0.050 ± 0.027

0.244 ± 0.074

Inflammation/innate immunity

 Ceruloplasmin, µmol/L

0.111 ± 0.034

0.023 ± 0.014

0.186 ± 0.028

0.374 ± 0.091

0.072 ± 0.034

 PROTt, g/L

1.785 ± 0.786

1.401 ± 0.883

17.964 ± 1.254

0.090 ± 0.044

0.066 ± 0.034

 Globulins, g/L

2.155 ± 0.955

1.636 ± 0.809

21.460 ± 2.059

0.091 ± 0.047

0.065 ± 0.033

Minerals

 Calcium, mmol/L

0.001 ± 0.001

0.002 ± 0.001

0.007 ± 0.001

0.125 ± 0.049

0.200 ± 0.073

 Potassium, mmol/L

0.026 ± 0.007

0.042 ± 0.018

0.079 ± 0.009

0.248 ± 0.057

0.286 ± 0.080

 Zinc, µmol/L

1.168 ± 0.444

2.377 ± 1.556

2.205 ± 0.377

0.346 ± 0.078

0.413 ± 0.092

  1. BHBA: β-hydroxybutyric acid; AST: aspartate aminotransferase; GGT: γ-glutamyl transferase; PON: paraoxonase; ROMt: total reactive oxygen metabolites; AOPP: advanced oxidation protein products; FRAP: ferric reducing antioxidant power; PROTt: total proteins
  2. \({\mathrm{h}}^{2}=\frac{{\upsigma }_{\mathrm{a}}^{2}}{{\upsigma }_{\mathrm{a}}^{2}+{\upsigma }_{\mathrm{e}}^{2}}\)
  3. \({\mathrm{h}}_{\mathrm{batch}}={\upsigma }_{\mathrm{batch}}^{2}/({\upsigma }_{\mathrm{a}}^{2}+{\upsigma }_{\mathrm{batch}}^{2}+{\upsigma }_{\mathrm{e}}^{2})\)
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Genetics Selection Evolution

ISSN: 1297-9686