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Table 3 Overlap of GWAS results across tibia traits, with their positions, estimated marker effects and p-values

From: Genetic markers associated with bone composition in Rhode Island Red laying hens

SNP position

Minor allele

Traits

Effect sizea

P-valueb

Chr

bp

1

107,054,728

A

Tibia strength, Tibia densityc

0.42, 0.40

2.7E−05, 3.7E−05

1

109,647,034

A

Medullary mineral %, Medullary phosphates/OMc

0.22, 0.24

8.0E−05, 2.3E−05

1

109,663,826

A

Medullary mineral %, Medullary phosphates/OMc

0.22, 0.24

8.0E−05, 2.3E−05

1

109,711,929

A

Medullary mineral %, Medullary phosphates/OMc

0.22, 0.24

8.0E−05, 2.3E−05

1

109,874,806

G

Medullary mineral %, Medullary phosphates/OMc

0.22, 0.24

9.0E−05, 2.7E−05

1

110,022,517

A

Medullary mineral %, Medullary phosphates/OMc

0.22, 0.24

5.6E−05, 1.5E−05

1

111,607,488

G

Tibia density, Medullary mineral %, Medullary phosphates/OMc

0.22, 0.22, 0.22

5.7E−05, 9.9E−05, 9.5E−05

1

111,673,836

A

Tibia density, TGA Medullary OM %d

0.24, − 0.23

2.7E−05, 7.7E−05

1

111,721,984

G

TGA Medullary OM %, Medullary mineral %, Medullary phosphates %, Medullary phosphates/OMd

− 0.23, 0.23, 0.22, 0.23

3.3E−05, 3.0E−05, 4.7E−05, 3.3E−05

1

111,798,225

A

Medullary mineral %, Medullary phosphates/OMc

0.25, 0.25

4.5E−05, 3.9E−05

1

111,807,107

A

TGA Medullary OM %, Medullary mineral %,Medullary phosphates %, Medullary phosphates/OMd

− 0.22, 0.24, 0.23, 0.25

8.9E−05, 1.9E−05, 4.5E−05, 1.9E−05

1

111,962,126

G

TGA Medullary OM %, Medullary mineral %d

− 0.22, 0.21

5.7E−05, 8.8E−05

1

113,308,308

A

TGA Medullary OM %, Medullary mineral %, Medullary phosphates/OMd

− 0.22, 0.21

5.7E−05, 8.8E−05

2

2,629,649

A

Tibia density, Cortical lipidd

0.24, − 0.26

8.8E-05, 3.2E−05

2

2,684,066

G

Tibia density, Cortical lipidd

0.24, − 0.26

8.8E−05, 3.2E−05

2

2,766,721

G

Tibia density, Cortical lipidd

0.25, − 0.25

5.0E−05, 3.9E−05

2

2,862,519

C

Tibia density, Cortical lipidd

0.25, − 0.25

5.0E−05, 3.9E−05

2

3,045,317

A

Tibia strength, Tibia density,Cortical lipidd

0.25, 0.25, − 0.24

7.6E−05, 2.7E−05, 7.9E−05

2

3,055,823

C

Tibia strength, Tibia density,Cortical lipidd

0.25, 0.25, − 0.24

7.6E−05, 2.7E−05, 7.9E−05

2

99,042,312

A

Cortical PO4/Amide I, TGA Cortical OM %c,e

0.30, 0.29

2.0E−05, 5.2E−05

3

27,204,115

G

Cortical lipid, TGA Cortical OM %c,e

0.30, 0.23

7.6E−08, 2.1E−05

3

27,351,346

C

Cortical lipid, TGA Cortical OM %c,e

0.29, 0.21

1.9E−07, 5.0E−05

3

27,434,588

G

Cortical lipid, TGA Cortical OM %c,e

0.31, 0.22

4.5E−08, 6.9E−05

4

83,057,186

A

Medullary PO4/Amide I, Medullary CO3/Amide Ic

0.26, 0.26

1.3E−06, 3.1E−06

4

83,154,195

G

Medullary PO4/Amide I, Medullary CO3/Amide Ic

0.21, 0.23

4.0E−05, 5.1E−06

  1. aAll traits were standardized (with zero mean and one standard deviation) to facilitate effect size interpretation
  2. bWald test P-value
  3. cCases of genetic marker affects different traits and the effects have the same direction
  4. dCases of genetic marker affects different traits and the effects have opposite directions
  5. eCases of overlapping between FTIR and TGA measurements