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Table 1 Timeline for the transmission trial

From: The WUR0000125 PRRS resilience SNP had no apparent effect on pigs’ infectivity and susceptibility in a novel transmission trial

  

Trial (day)

Shedder (dpc_S)

Contact (dpc_C)

Event

Step 1

A

0

  

Direct infection of Inoculation pigs

1

0

 

Sample, transfer Inoculation pigs; introduce naïve Shedder pigs

2

1

 

B

3

2

 

4

3

 

5

4

 

6

5

 

Sample Inoculation and Shedder pigs

Step 2

A

7

6

0

Transfer infected Shedder pigs; introduce naïve Contact pigs

8

7

1

Sample Shedder pigs

9

8

2

Sample Contact pigs

10

9

3

Sample Shedder pigs

11

10

4

12

11

5

13

12

6

B

14

13

7

Remove Shedder pigs; sample Shedder & Contact pigs

15

14

8

16

15

9

17

16

10

Sample Contact pigs

18

17

11

Termination of trial

  1. Timing of events carried out during the 18 day trial, standardised for Shedder pigs (S) and Contact pigs (C) for the time (days) since exposure to infected donors (days post contact (dpc)). Step 1, Infection of the Shedder pigs Step 1A, direct infection of the Inoculation pigs; Step 1B, infection of Shedder pigs through natural transmission; Step 2, Main transmission trial (Step 2A, naturally infected Shedder pigs introduced to naive Contact pigs; Step 2B, Shedder pigs removed); dpc_S, for Shedder pigs, days post contact from directly infected Inoculation pigs; dpc_C, for Contact pigs, days post contact from naturally infected Shedder pigs. Sample refers to serum and nasal swab samples taken. Sample dates are highlighted in italics. -, no event