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Fig. 8 | Genetics Selection Evolution

Fig. 8

From: Genomic prediction based on selective linkage disequilibrium pruning of low-coverage whole-genome sequence variants in a pure Duroc population

Fig. 8

Manhattan plot of genome-wide association analysis for six simulated traits in the discovery population. Simulated QTN and other SNPs are colored by red and gray points, respectively. The blue dotted line represents the P-value threshold 5 × 10–8, 10–4, 0.001, 0.01 from top to bottom. The number of QTN detected and the estimated false-positive rate for each P-value threshold are shown in Additional file 10: Table S5. a QTN_100_h2_0.15 simulated traits with 100 QTN and a heritability of 0.15, b QTN_10000_h2_0.15 simulated traits with 10,000 QTN and a heritability of 0.15, c QTN_100_h2_0.30 simulated traits with 100 QTN and a heritability of 0.30, d QTN_10000_h2_0.30 simulated traits with 10,000 QTN and a heritability of 0.30, e QTN_100_h2_0.60 simulated traits with 100 QTN and a heritability of 0.60, f QTN_10000_h2_0.60 simulated traits with 10,000 QTN and a heritability of 0.60. The result shows the difficulty in detecting most QTN by GWAS, especially for the low-heritability trait

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Genetics Selection Evolution

ISSN: 1297-9686