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Fig. 7 | Genetics Selection Evolution

Fig. 7

From: A cautionary tale of low-pass sequencing and imputation with respect to haplotype accuracy

Fig. 7

Example of the impact of sequencing depth on genotype imputation accuracy. a A matrix of pre-imputation genotypes for a single dog (LAB_11) for the genomic region 18:41493468–41495040. b A matrix of post-imputation genotypes for the same region and dog for each of the reference panels used. The genotypes are consistent across reference panels, but differ at some variants across sequencing depths, for instance the two variants annotated with X each return three possible genotypes. c A matrix of variant IMPUTE INFO scores for the same region and dog for each of the reference panels used. The INFO score is on a scale of 0 to 1, with 1 indicating a high certainty of imputed genotype accuracy

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