Fig. 2

Estimated inbreeding effects (a) and associated significance levels (b) for 100 simulations. Each replicate was simulated under the assumption that all HBD classes have the same effect (− 21). Partitioning of autozygosity in different HBD classes was performed with medium-density genotyping data (~ 30K SNPs). The counts on the right of each panel represent the number of simulations with higher effects than the value estimated in the real data (a) or the number of simulations with significant association (b)