Identification of candidate regulatory genes for intramuscular fatty acid composition in pigs by transcriptome analysis

Table 2 RIF analysis with 19 significant TF^a identified by RIF1 or RIF2 metrics according to extreme FA profiles and gene expression in BC1_DU pigs

TF	Gene description	Family	Avgexpr^b	RIF1	RIF2
TADA2A	Transcriptional adaptor 2A	MYB	4.11	− 2.09	1.44
MBD2	Methyl-CpG binding domain protein 2	MBD	4.90	− 1.43	− 1.44
SIX5	SIX homeobox 5	Homeobox	2.38	− 0.83	− 1.30
TERF1	Telomeric repeat binding factor 1	MYB	3.21	1.63	− 1.28
CEBPG	CCAAT enhancer binding protein gamma	TF_bZIP	4.96	1.49	− 1.15
HBP1	HMG-box transcription factor 1	HMG	6.12	− 0.89	1.12
FOXJ3	Forkhead box J3	Fork_head	6.36	− 0.54	1.09
CARHSP1	Calcium regulated heat stable protein 1	CSD	3.37	1.86	0.82
MAF	MAF bZIP transcription factor	TF_bZIP	7.19	0.39	− 0.68
TFAM	Transcription factor A, mitochondrial	HMG	4.79	0.82	− 0.52
KLF10	Kruppel like factor 10	zf-C2H2	6.24	− 0.32	1.53
YBX2	Y-box binding protein 2	CSD	4.22	− 0.38	− 1.06
ZNF407	Zinc finger protein 407	zf-C2H2	3.74	0.10	0.95
ZNF524	Zinc finger protein 524	zf-C2H2	4.84	0.13	0.73
PAX7	Paired box 7	PAX	2.72	− 0.28	0.46
ZNF326	Zinc finger protein 326	Others	5.56	0.35	− 0.45
LBX1	Ladybird homeobox 1	Homeobox	3.53	0.38	− 0.21
MAFA	MAF bZIP transcription factor A	TF_bZIP	3.23	− 0.19	− 0.09
ZNF146	Zinc finger protein 146	zf-C2H2	3.46	− 0.20	0.03

^aThe 19 TF belong to 10 different families
^bThe expression average (in log2 CPM) for each TF is indicated by avgexpr variable

ISSN: 1297-9686