A common regulatory haplotype doubles lactoferrin concentration in milk

Table 5 Correlations between the LTF eQTL and neighbouring ChIP-seq and ATAC-seq QTL within 1 Mbp of the LTF gene

Peak name	Location (BTA22)	\(\beta\) allele affects		\(-\log _{10}(p)\)
		Pearson	Spearman	Pearson	Spearman
Me1-196	52960027–52962680	0.834	0.851	0.966	0.969
Me1-202	52981401–52984701	0.781	0.735	0.848	0.813
Me3-213	52580146–52580284	− 0.688	− 0.788	0.892	0.855
ATAC-92	52940691–52941040	0.818	0.559	0.845	0.736
ATAC-93	52946446–52948019	0.909	0.833	0.908	0.883
ATAC-94	52953062–52954626	0.869	0.667	0.890	0.840
ATAC-113	53055448–53055807	− 0.631	− 0.619	0.854	0.815
ATAC-194	53809923–53810456	− 0.808	− 0.763	0.640	0.576

Both Pearson and Spearman (rank) correlations were calculated between both the QTL allele effects, and the log-scale p-values. Only hQTL and caQTL with a minimum \(p<{1\times 10^{-5}}\) and an absolute correlation \(\mathsf {>0.8}\) for at least one statistic are included. Correlations were calculated across markers within 50 kb of the LTF gene, i.e., between positions 52896110 and 53036647 on BTA22

ISSN: 1297-9686