A note on QTL detecting for censored traits
© INRA, EDP Sciences 2006
Received: 9 August 2005
Accepted: 6 October 2005
Published: 24 February 2006
Most existing statistical methods for mapping quantitative trait loci (QTL) assume that the phenotype follows a normal distribution and that it is fully observed. However, some phenotypes have skewed distributions and may be censored. This note proposes a simple and efficient approach to QTL detecting for censored traits with the Cox PH model without estimating the baseline hazard function which is "nuisance".
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