Open Access

Individual increase in inbreeding allows estimating effective sizes from pedigrees

  • Juan Pablo Gutiérrez1Email author,
  • Isabel Cervantes1,
  • Antonio Molina2,
  • Mercedes Valera3 and
  • Félix Goyache4
Genetics Selection Evolution200840:359

https://doi.org/10.1186/1297-9686-40-4-359

Received: 14 May 2007

Accepted: 9 January 2008

Published: 15 July 2008

Abstract

We present here a simple approach to obtain reliable estimates of the effective population size in real world populations via the computation of the increase in inbreeding for each individual (delta F i ) in a given population. The values of delta F i are computed as t-root of 1 - (1 - F i ) where F i is the inbreeding coefficient and t is the equivalent complete generations for each individual. The values of delta F computed for a pre-defined reference subset can be averaged and used to estimate effective size. A standard error of this estimate of Ne can be further computed from the standard deviation of the individual increase in inbreeding. The methodology is demonstrated by applying it to several simulated examples and to a real pedigree in which other methodologies fail when considering reference subpopulations. The main characteristics of the approach and its possible use are discussed both for predictive purposes and for analyzing genealogies.

Keywords

effective size increase in inbreeding overlapped generation genetic contribution

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Authors’ Affiliations

(1)
Departamento de Producción Animal, Facultad de Veterinaria
(2)
Departamento de Genética, Universidad de Córdoba
(3)
Departamento de Ciencias Agro-Forestales, EUITA, Universidad de Sevilla
(4)
SERIDA-Somió

Copyright

© INRA, EDP Sciences 2008

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