Mapping quantitative trait loci (QTL) in sheep. I. A new male framework linkage map and QTL for growth rate and body weight

Table 4 Summary of QTL results for growth rates across different phases of growth

Growth Rate Trait	OAR	LOD with Ranked P-value	QTL Position	Closest Marker	Std QTL Effect for Female	Std QTL Effect for Male	Sex × QTL Interaction P-value	1-LOD Support Interval
GR00-43	1	2.33*	118	BM4129	0.048	0.624	0.019	99.5 – 153.5
	3	2.87**	28	OARCP34	-0.165	0.737	0.001	11.0 – 52.0
	6	4.16***	62	OARHH55	0.242	0.767	0.029	38.9 – 78.9
	8	2.02*	77	KD101	0.199	-0.584	0.034	56.4 – 94.4
	11	3.96***	55	BM17132	0.305	0.905	0.028	44.3 – 67.3
	21	2.62*	26	CSSM13	0.109	0.584	0.160	5.0 – 78.0
	24	3.30***	86	DIK2568	-0.158	0.599	0.001	80.1 – 100.1
GR43-56	1	2.47*	357	BMS1789	-0.038	-0.622	0.015	348.5 – 376.5
	3	3.33***	39	OARCP34	-0.092	0.643	0.001	17.0 – 51.0
	6	3.86***	60	OARHH55	0.350	0.679	0.228	36.9 – 75.9
	11	4.60****	54	BM17132	0.346	0.970	0.022	43.3 – 64.3
	21	4.04***	27	CSSM13	0.091	0.716	0.007	10.0 – 35.0
	24	3.14***	85	DIK2568	-0.096	0.587	0.003	76.1 – 97.1
	26	2.00*	63	OARJMP23	0.056	0.461	0.054	49.0 – 62.5
GR56-83	1	2.44*	357	BMS1789	-0.039	-0.620	0.016	347.5 – 379.5
	3	3.05*	105	DIK4796	0.015	0.575	0.033	94.0 – 116.0
	6	2.84*	50	BM1329	0.493	0.428	0.794	33.9 – 75.9
	11	2.77*	53	BM17132	0.298	0.732	0.126	37.3 – 70.3
	21	3.08*	29	CSSM13	0.108	0.597	0.030	12.0 – 35.0
	24	2.47*	85	DIK2568	-0.053	0.538	0.010	69.1 – 98.1
	26	2.37*	63	OARJMP23	0.147	0.483	0.110	49.0 – 62.5
GR83-98	11	2.95**	29	HEL10	NA	0.860	NA	29.3 – 43.3
	23	2.06*	40	MCMA1	NA	0.901	NA	20.5 – 83.0

Growth rates are not adjusted for the body weight at the start of the phase; GRxx-yy refers to the growth rate in the interval xx-yy; models fitted are of the form 'Sex + QTL + Sex.QTL', except for week 98 (wethers only) for which the model was 'QTL' only. P-values were obtained from likelihood ratio tests (LRT) with 2 df (testing QTL + Sex.QTL) or 1 df (QTL only, in week 98); these P-values were adjusted for false discovery using the method outlined in Benjamini and Hochberg [42] with *P < 0.05, **P < 0.001, ***P < 0.005, ****P < 0.0001; standardized QTL effects are expressed as the estimated effect difference (Awassi – Merino) relative to the estimated residual standard deviation

ISSN: 1297-9686