Mapping quantitative trait loci (QTL) in sheep. I. A new male framework linkage map and QTL for growth rate and body weight

Table 5 Summary of QTL results for growth rates across different phases of growth

Growth Rate Trait	OAR	LOD with Ranked P-value	QTL Position	Closest Marker	Std QTL Effect for Female (A-M)^†	Std QTL Effect for Male (A-M)^†	Sex × QTL Interaction P-value	1-LOD Support Interval
GR00-43 adj for BW02	1	2.75*	357	BMS1789	-0.085	-0.707	0.022	346.5 – 373.5
	6	3.06**	43	BM1329	0.387	0.590	0.425	21.9 – 72.9
	11	5.23***	56	BM17132	0.328	0.959	0.017	45.3 – 67.3
	12	2.20*	104	HUJ625	-0.232	0.561	0.003	84-3 – 118.0
	16	2.19*	98	DIK4612	-0.148	-0.454	0.166	85.0 – 110.0
	21	2.27*	19	CSSM013	0.203	0.542	0.162	0.0 – 53.0
	24	2.05*	91	DIK2568	-0.158	0.494	0.009	80.1 – 104.7
GR43-56 adj for BW43	NS
GR56-83 adj for BW56	3	3.41***	105	DIK4796	0.151	0.584	0.040	96.0 – 113.0
	7	2.62*	100	TGLA444	0.524	-0.124	0.017	90.0 – 122.2
	18	2.14*	72	BM7243	-0.100	0.474	0.009	61.1 – 85.1
GR83-98 adj for BW83	1	2.59*	48	BMS835	NA	0.871	NA	32.5 – 67.7

Growth rates are adjusted for the body weight at the start of the phase. GRxx-yy refers to the growth rate in the interval xx-yy and BWxx is the body weight at week xx; Models fitted are of the form 'BWxx + Sex + QTL + Sex.QTL', except for week 98 (wethers only) for which the model was 'BWxx + QTL' only; P-values were obtained from likelihood ratio tests (LRT) with 2 df (testing QTL + Sex.QTL) or 1 df (QTL only, in Week 98); these P-values were adjusted for false discovery using the method outlined in Benjamini and Hochberg [42] with *P < 0.05, **P < 0.001, ***P < 0.005, ****P < 0.0001; standardized QTL effects are expressed as the estimated effect difference (Awassi – Merino) relative to the estimated residual standard deviation

ISSN: 1297-9686