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Table 4 Enrichment of gene categories in different tissue modules for NEFA, HDL-C, triglyceride, glucose and ALT levels

From: Association between plasma metabolites and gene expression profiles in five porcine endocrine tissues

Metabolite FATB GONA AHYP THYG HYPO
Glucose   RNA binding and splicing    
NEFA oxidation reduction
biosynthesis of unsaturated fatty acid
coenzyme binding
mitochondrion
regulations of protein, nucleotide metabolism
cell-cell signaling
T cell proliferation
synaptic transmission
muscle and skeletal development
behavior
protein transport and localization
calcium ion binding
neuron projection
presynaptic membrane
contractile fiber
dendritic shaft
  protein transport
learning and memory
proton transporting
ATPase complex
synapse;
dendritic shaft
cell junction
HDL-C lipoprotein particle    RNA processing; ribosome RNA splicing
Triglyceride     Alzheimer's disease
monosaccharide catabolic process
 
ALT   tight junction
cell adhesion
leukocyte transendothelial migration
nucleoside triphosphate metabolic process
blood vessel development
regulation of cell motion
polysaccharide and heparin binding
  ECM receptor interaction
focal adhesion
cell motion
neuron differentiation
cell-cell signaling
muscle, heart and bone development
regulation of transcription and metabolic processes
response to wounding
learning and memory
 
  1. Non-esterified fatty acids (NEFA); alanine aminotransferase (ALT); backfat (FATB);, gonad (GONA); adenohypophysis (AHYP); thyroid (THYG); hypothalamus (HYPO)