Table 4 Enrichment of gene categories in different tissue modules for NEFA, HDL-C, triglyceride, glucose and ALT levels
Metabolite | FATB | GONA | AHYP | THYG | HYPO |
|---|---|---|---|---|---|
Glucose | RNA binding and splicing | ||||
NEFA | oxidation reduction biosynthesis of unsaturated fatty acid coenzyme binding mitochondrion | regulations of protein, nucleotide metabolism cell-cell signaling T cell proliferation synaptic transmission muscle and skeletal development behavior | protein transport and localization calcium ion binding neuron projection presynaptic membrane contractile fiber dendritic shaft | protein transport learning and memory proton transporting ATPase complex synapse; dendritic shaft cell junction | |
HDL-C | lipoprotein particle | RNA processing; ribosome | RNA splicing | ||
Triglyceride | Alzheimer's disease monosaccharide catabolic process | ||||
ALT | tight junction cell adhesion leukocyte transendothelial migration nucleoside triphosphate metabolic process blood vessel development regulation of cell motion polysaccharide and heparin binding | ECM receptor interaction focal adhesion cell motion neuron differentiation cell-cell signaling muscle, heart and bone development regulation of transcription and metabolic processes response to wounding learning and memory |