Genome-wide interval mapping using SNPs identifies new QTL for growth, body composition and several physiological variables in an F2 intercross between fat and lean chicken lines

Table 5 Results of multiple QTL analysis

Trait	GGA	QTL1 Loc (cM)	QTL1 nearest markers	QTL2 Loc (cM)	QTL2 nearest markers	H0 vs H2 SL	H1 vs H2 SL	QTL1 effect	HS	QTL2 effect	HS	Ref
BMP	3	39	rs16225707- rs14316721	249	rs15452125- rs14410153	*		0.59 ± 0.30	2	0.75 ± 0.47	2	[29]
BW3	3	96	rs14334468- rs15316026	264	rs15457054- rs15459111	*		0.51 ± 0.16	3	0.54 ± 0.07	2	-
BW5	3	96	rs14334468- rs15316026	252	rs15452125- rs14410153		**	0.66 ± 0.13	2	0.52 ± 0.21	4	[28, 30]
BW7	3	96	rs14334468- rs15316026	249	rs15452125- rs14410153		*	0.64 ± 0.20	2	0.65 ± 0.26	3	-
BW7	4	132	rs15595474- RBL4469	150	MCW0240- rs14488074		*	0.57 ± 0.19	5	0.72 ± 0.41	4	[29]
BMW maj	5	122	rs15731150- rs15733056	130	rs15733400- rs14551368	*		0.93 ± 0.12	2	0.60 ± 0.27	5	[35]
BMP	5	122	rs15731150- rs15733056	130	rs15733400- rs14551368	*		0.71 ± 0.40	3	0.62 ± 0.24	5	-
ThW	8	10	rs14635367- rs15900903	59	rs14648254- rs15925157		*	0.62 ± 0.15	2	0.49 ± 0.15	3	-
BW3	9	67	rs15979233- RBL4169	76	rs15981733- rs13735709	*		0.72 ± 0.43	4	0.69 ± 0.40	4	-
BMW maj	12	29	rs13610024- rs14036782	50	rs14981507- rs14043099	*		0.57 ± 0.20	4	0.65 ± 0.18	3	-
BMP	12	29	rs13610024- rs14036782	50	rs14981507- rs14043099	*		0.62 ± 0.21	4	0.56 ± 0.21	4	-
BW3	18	14	rs15813867- rs15037317	37	rs15826197- rs14112762	*		0.48 ± 0.15	4	0.65 ± 0.30	2	-

Traits are described in Table 1; GGA Gallus gallus chromosome, Loc location, SL significance level with * at 5% and ** at 1% chromosome-wide, QTL locations in bold, QTLs previously detected in single-QTL analysis, QTL effect substitution effect expressed in phenotypic standard deviation. HS number of heterozygous sires out of 5. Ref publications describing similar QTL affecting the same trait and presenting a similar genomic location.

ISSN: 1297-9686