Genome-wide association study of footrot in Texel sheep

Table 2 Chromosome-wise significant (p < 0.05) SNPs associated with footrot

Chr	SNP	Position (bp)	Model*	-log10 (p-value)	Variance explained ^‡	Nearest gene		Function
Chr	SNP	Position (bp)	Model*	-log10 (p-value)	Variance explained ^‡	Name	Distance ^† (bp)	Function
4	s55696.1	66980883	R	4.77	0.054	CPVL	between exons 2 & 3	carboxypeptidase, vitellogenic-like protein
8	OAR8_77678255.1	72284055	A	4.59	0.052	HNRPDL	455966	heterogeneous nuclear ribonucleoprotein D-like
8	OAR8_77678255.1	72284055	A	4.59	0.052	Uncharacterised (72529599–72531004)	−245544	unknown
14	s53098.1	8589373	R	4.50	0.051	Uncharacterised (8581480–8673246)	between exons 1 & 2	unknown
17	OAR17_29456634.1	26848221	R	4.52	0.051	Uncharacterised (26721069–26722410)	125811	unknown
18	OAR18_23478564.1	23886219	A	4.88	0.056	Uncharacterised (23697715–23776771)	109448	unknown
18	OAR18_23478564.1	23886219	D	5.65	0.065	MORF4L1	−288749	mortality factor 4 like 1
24	s34109.1	962868	D	4.35	0.049	Uncharacterised (961975–993337)	between exons 8 & 7	unknown
26	OAR26_8299529.1	6166783	R	4.50	0.051	GPM6A	24644	glycoprotein M6A
26	OAR26_8299529.1	6166783	R	4.50	0.051	Uncharacterised (6232840–6233142)	−66057	unknown

† Positive value denotes the gene located downstream of SNP, negative value denotes the gene located upstream of SNP.
‡ proportion of variance explained by the SNP.
* A – additive; R – recessive; D – dominant model.

ISSN: 1297-9686