Multi-breed genome-wide association study reveals novel loci associated with the weight of internal organs

Table 2 Genome-wide significant QTL identified by GWAS for the weight of four internal organs and carcass in five populations

Trait	Chr	Population	Nb_snp	Top SNP	Position (bp)	p value	Var (%)	Candidate gene
Heart weight	2	F₂	17	rs81318741	920,370	2.00E−10	8.6	IGF2
	4	Laiwu	20	rs80991149	77,161,841	2.05E−07	8.7
	7	F₂	25	rs80935535	34,803,564	1.48E−09	13.2	GRM4, HMGA1
	10	DLY	1	rs81334236	32,207,568	9.05E−07	3.2
Liver weight	7	F₂	95	rs80935535	34,803,564	1.91E−10	13.2	GRM4, HMGA1
Liver weight		Laiwu	25	rs80917438	40,398,610	6.20E−08	10.7
Spleen weight	5	DLY	1	rs81303231	95,090,653	3.54E−07	5.5
Spleen weight	7	Erhualian	1	rs80965843	97,889,360	3.05E−07	2.6
Carcass weight	11	Sutai	1	rs81000302	48,894,442	9.95E−08	16.1

Chr chromosome number, Nb _snp number of SNPs that reached the suggestive significance level, Var (%) % of phenotypic variance explained by the top SNP

ISSN: 1297-9686