A genome-wide association study for genetic susceptibility to Mycobacterium bovis infection in dairy cattle identifies a susceptibility QTL on chromosome 23

Table 3 Genes identified, within QTL identified using the Bayesian approach applied to GWAS

Chr^a	Gene name	SNP name	Bayes factor	MAF	QTL length
1	KALRN	BovineHD0100019801	57.58	0.33	12,165
1	TMPRSS2	BovineHD0100041198	23.41	0.12	3575
2	TMEFF2	BovineHD0200023336	29.83	0.43	22,453
3	NFIA	BovineHD0300025132	26.77	0.41	17,003
		BovineHD0300024222	22.78	0.39
3	TMEM125	ARS-BFGL-NGS-114804	20.69	0.39	28,366
4	PTN	BovineHD4100003190	30.57	0.41	6142
5	DENND5B	BovineHD0500022394	38.49	0.49	30,818
		BovineHD0500022395	20.38	0.49
6	PGM2	BovineHD0600016172	51.47	0.42	62,372
		BovineHD0600016181	49.70	0.43
6	LIMCH1	BovineHD0600017122	20.69	0.21	31,027
6	SLC4A4	BovineHD0600024174	35.37	0.34	6800
8	PGM5	BovineHD0800013359	21.01	0.47	16,615
10	AP3B1	BovineHD1000002985	41.29	0.24	13,726
14	CPSF1, ADCK5, SLC52A2	BovineHD1400000249	134.16	0.48	266,275
	SCRT1, DGAT1, HSF1,	BovineHD1400000246	37.41	0.48
	MROH1, MIR1839, MAF1	BovineHD1400000246	37.41	0.48
	SHARPIN, CYC1, GPAA1,
	EXOSC4, OPLAH
17	OSBP2	BovineHD1700020903	41.62	0.26	22,175
		BovineHD1700020906	28.88	0.26
		BovineHD1700020907	28.88	0.26
		BovineHD1700020908	22.36	0.26
17	RNF185	BovineHD1700021001	285.55	0.32	3141
18	SLC6A2	ARS-BFGL-NGS-2712	20.07	0.096	12,244
18	KCNK6	BovineHD1800014284	28.46	0.26	101,126
20	SDF2, SUPT6H, PROCA1,	BovineHD2000019220	28.46	0.41	36,609
	RAB34, RPL23A, TLCD1,	BovineHD2000019231	23.72	0.41
	NEK8, TRAF4	BovineHD2000019229	20.69	0.41
23	FKBP5	Hapmap50596-BTA-121389	21.74	0.13	74,693
29	ME3	BovineHD2900002648	26.14	0.45	1263

Chromosome, name of SNPs with a significant Bayes factor within QTL regions, Bayes factor, minor allele frequency (MAF) and QTL size
^aChromosome number

ISSN: 1297-9686