Fig. 4

IBD analysis around the RP1 frameshift mutation. Blue line number of animals carrying the RP1 frameshift allele but showing at least 5 % of homozygous genotypes for the alternative allele as compared with the RP1 Fs/Fs Normande bull Diametre in sliding windows of 100 SNPs. Thirty-five Fs/Wt and three Fs/Fs animals were considered. Successive windows around the mutation for which this count is null defines an 88.6-kb IBD segment common to all carriers. The same calculation was applied to a control group of 38 randomly chosen non-carrier bulls from the same breeds (red dashed line). Note that the segment around the mutation is not conserved in this group. The black dashed line indicates the localization of the mutation