A reverse genetic approach identifies an ancestral frameshift mutation in RP1 causing recessive progressive retinal degeneration in European cattle breeds

Table 3 Results of the ocular tests for the Normande dairy cattle examined

	Fs/Fs	Fs/Wt	Wt/Wt
Normal vision and eyes fundus	2 (<2 years)	7 (6.1 years)	7 (5.7 years)
Mild unilateral or bilateral focal retinal degeneration with preserved vision		2 (5.8 years)	3 (7.2 years)
Bilateral retinal degeneration with marked visual deficit	1 (4.5 years)
Bilateral retinal degeneration with blindness	1 (5.5 years)
Number of animals	4	9	10

Note that the pupillary light reflex was preserved in all the animals studied. The number of animals for each group and their average age in years (y) are presented
Fs frameshift allele, Wt wild type allele

ISSN: 1297-9686