Combined GWAS and ‘guilt by association’-based prioritization analysis identifies functional candidate genes for body size in sheep

Table 5 List of prioritized ovine genes based on guilt by association prioritization analysis

Gene	Overall rank^a	Rank in SNP	p value^b	Chr^c	Marker	Minimum^d distance (kb)	PC^e
TP53	1	1	0.003	11	s49406.1	338	2
BMPR1A	2	1	0.005	25	s16706.1	353	1
PIK3R5	3	2	0.007	11	s49406.1	635	2
RPL26	4	3	0.008	11	s49406.1	254	2
PRKDC	5	1	0.009	9	OAR9_32819540.1	876	2
NODAL	6	1	0.01	25	s09443.1	69	1
PRF1	7	2	0.01	25	s09443.1	220	1
COL13A1	8	3	0.014	25	s09443.1	318	1
HK1	9	4	0.014	25	s09443.1	816	1
APAF1	10	1	0.014	3	s19829.1	696	3
MYH10	11	4	0.014	11	s49406.1	339	2
POLR2A	12	5	0.017	11	s49406.1	482	2
DVL2	13	6	0.017	11	s49406.1	707	2
CHRNB1	14	7	0.02	11	s49406.1	523	2
CTC1	15	8	0.021	11	s49406.1	123	2
AHI1	16	1	0.021	8	OAR8_65677467.1	371	1
SLC2A4	17	9	0.023	11	s49406.1	665	2
LDB3	18	2	0.023	25	s16706.1	273	1
PEX7	19	2	0.024	8	OAR8_65677467.1	914	1
GUCY2D	20	10	0.025	11	s49406.1	48	2
MAP3K5	21	3	0.026	8	OAR8_65677467.1	654	1
NHLRC1	22	1	0.028	20	OAR20_41133825.1	709	1
EIF4A1	23	11	0.028	11	s49406.1	414	2
ALOXE3	24	12	0.028	11	s49406.1	15	2
FHIT	25	1	0.029	19	OAR19_41234161.1	785	3
NTN1	26	13	0.031	11	s49406.1	744	2
HES7	27	14	0.035	11	s49406.1	39	2
TMEM107	28	15	0.036	11	s49406.1	95	2
PSMA8	29	1	0.036	23	OAR23_33457070.1	813	2
ATP1B2	30	16	0.036	11	s49406.1	355	2
ACADVL	31	17	0.036	11	s49406.1	715	2
FGF11	32	18	0.037	11	s49406.1	533	2
MYB	33	4	0.037	8	OAR8_65677467.1	655	1
TNFSF12	34	19	0.038	11	s49406.1	434	2
TNK1	35	20	0.04	11	s49406.1	582	2
ADAMTS14	36	5	0.041	25	s09443.1	265	1
ALOX12B	37	21	0.042	11	s49406.1	0	2
MMRN2	38	3	0.044	25	s16706.1	500	1
ZNF521	39	2	0.049	23	OAR23_33457070.1	0	2

ISSN: 1297-9686