A model to estimate effects of SNPs on host susceptibility and infectivity for an endemic infectious disease

Table 6 Basic reproduction ratio and prevalence for different susceptibility effects

Value susceptibility allele G (γ _G)	Transmission rate parameters for reference type (c)^a	Basic reproduction ratio^b		Prevalence
		Basic reproduction ratio^b		Total	Per susceptibility genotype
		Classic (\(R_{0}\))	Equilibrium (\(R\))	Total	\(GG\)	\(Gg\)	\(gg\)
0.3	0.8	3.00	2.10	0.52	0.25	0.53	0.79
0.4	0.6	3.03	2.39	0.58	0.36	0.59	0.78
0.5	0.45	3.00	2.59	0.61	0.45	0.62	0.77
0.6	0.35	3.01	2.77	0.64	0.52	0.64	0.75
0.7	0.28	3.07	2.94	0.66	0.58	0.66	0.74
0.8	0.22	3.03	2.98	0.66	0.61	0.67	0.71
0.9	0.18	3.08	3.07	0.67	0.65	0.67	0.70
1.0	0.145	3.045	3.045	0.67	0.67	0.67	0.67

^aReference genotype is ggff
^b p _g = p _f = 0.5, α = 0.0476, \(\gamma_{g} = \varphi_{f} = 1\) and \(\varphi_{F} = \gamma_{G}\)

ISSN: 1297-9686