Within-breed and multi-breed GWAS on imputed whole-genome sequence variants reveal candidate mutations affecting milk protein composition in dairy cattle

Table 4 Number of variants with genome-wide significant effects (−log₁₀ (P) > 8.4) for milk composition traits in within-and multi-breed analyses

Trait	Within-breed analyses				Multi-breed analyses
Trait	MON^a	NOR^a	HOL^a	Shared among three breeds	Multi-breed analyses
PC	1905	1201	2394	0	2350
α-LA	4590	6490	8248	213	7224
β-LG	19,952	16,048	15,517	2266	18,612
α_s1-CN	2232	708	629	182	2280
α_s2-CN	866	193	636	1	1947
β-CN	665	734	524	96	1652
κ-CN	4110	5878	6532	553	7012
\(\varSigma\)-CN	13,920	8716	11,833	961	12,698
\(\varSigma\)-WP	16,583	13,126	15,327	1916	16,546
Total number of distinct variants	29,722	27,787	30,988	3080	34,248

ISSN: 1297-9686