Table 2 Details on ECA11 candidate non-synonymous SNPs
Position (bp) | Ref. allele | Alternate allele | Gene | Protein accession number | Consequence | SIFT |
|---|---|---|---|---|---|---|
21,891,160 | G | A | KRT25 | ENSECAP00000011587 | p.R89H | Deleterious p = 0.01 |
21,932,167 | G | T | KRT24 | ENSECAP00000013915 | p.G51C | Tolerated p = 0.05 |
22,186,465 | C | T | TOP2A | ENSECAP00000011684 | p.S1088L | Deleterious p = 0.05 |
22,191,762 | G | T | TOP2A | ENSECAP00000011684 | p.L1284F | Deleterious p = 0.01 |