Table 6 List of ontology terms that were significantly over- and underrepresented in the set of genes located in 1-Mb windows that were identified for at least one temperature-humidity index category comparison
From: Genome-wide association of changes in swine feeding behaviour due to heat stress
Ontology term | Gene set | ||||
|---|---|---|---|---|---|
Annotated genesa (n = 21,324) | Genesb (n = 254) | Number of genes expected | Over (+) or under (−) represented | p value | |
Biological process | |||||
Positive regulation of peptidyl-serine phosphorylation of STAT protein | 36 | 10 | 0.43 | + | 2.37E−07 |
Natural killer cell activation involved in immune response | 37 | 10 | 0.45 | + | 3.08E−07 |
Regulation of peptidyl-serine phosphorylation of STAT protein perception | 38 | 10 | 0.46 | + | 3.98E−07 |
B cell proliferation | 48 | 10 | 0.58 | + | 3.70E−06 |
Natural killer cell activation | 50 | 10 | 0.60 | + | 5.45E−06 |
Response to exogenous dsRNA | 51 | 10 | 0.61 | + | 6.58E−06 |
T cell activation involved in immune response | 56 | 10 | 0.67 | + | 1.59E−05 |
Mononuclear cell proliferation | 73 | 11 | 0.88 | + | 1.44E−05 |
Lymphocyte proliferation | 73 | 11 | 0.88 | + | 1.44E−05 |
Leukocyte proliferation | 77 | 11 | 0.93 | + | 2.49E−05 |
Response to dsRNA | 72 | 10 | 0.87 | + | 1.66E−04 |
Positive regulation of peptidyl-serine phosphorylation | 88 | 11 | 1.06 | + | 9.63E−05 |
Defense response to virus | 110 | 13 | 1.33 | + | 9.08E−06 |
Lymphocyte activation involved in immune response | 88 | 10 | 1.06 | + | 1.04E−03 |
B cell differentiation | 89 | 10 | 1.07 | + | 1.16E−03 |
Regulation of peptidyl-serine phosphorylation | 112 | 12 | 1.35 | + | 1.14E−04 |
Humoral immune response | 96 | 10 | 1.16 | + | 2.29E−03 |
Leukocyte activation involved in immune response | 111 | 12 | 1.34 | + | 8.36E−03 |
Cell activation involved in immune response | 113 | 10 | 1.36 | + | 9.79E−03 |
Adaptive immune response | 137 | 12 | 1.65 | + | 9.80E−04 |
T cell activation | 161 | 14 | 1.94 | + | 9.81E−05 |
B cell activation | 117 | 10 | 1.41 | + | 1.33E−02 |
Response to virus | 158 | 13 | 1.90 | + | 6.05E−04 |
Regulation of STAT cascade | 125 | 10 | 1.51 | + | 2.37E−02 |
Regulation of JAK-STAT cascade | 125 | 10 | 1.51 | + | 2.37E−02 |
Lymphocyte differentiation | 171 | 12 | 2.06 | + | 9.79E−03 |
Lymphocyte activation | 241 | 15 | 2.90 | + | 2.17E−03 |
Leukocyte differentiation | 230 | 14 | 2.77 | + | 6.96E−03 |
Cell proliferation | 322 | 19 | 3.88 | + | 1.33E−04 |
Immune effector process | 257 | 15 | 3.10 | + | 4.81E−03 |
Response to organic cyclic compound | 377 | 20 | 4.54 | + | 3.13E−04 |
Defense response to other organism | 264 | 14 | 3.18 | + | 3.34E−02 |
Leukocyte activation | 284 | 15 | 3.42 | + | 1.62E−02 |
Cell activation | 357 | 18 | 4.30 | + | 3.08E−03 |
Response to nitrogen compound | 471 | 21 | 5.68 | + | 2.47E−03 |
Response to organic substance | 1460 | 43 | 17.60 | + | 3.57E−04 |
Cell differentiation | 2021 | 49 | 24.36 | + | 1.22E−02 |
Cellular developmental process | 2077 | 49 | 25.03 | + | 2.59E−02 |
Developmental process | 3175 | 67 | 38.27 | + | 1.45E−02 |
Sensory perception | 1326 | 1 | 15.98 | – | 7.80E−03 |
Molecular function | |||||
Type I interferon receptor binding | 32 | 10 | 0.39 | + | 2.61E−08 |
Glutathione transferase activity | 27 | 5 | 0.33 | + | 4.88E−02 |
Cytokine activity | 177 | 17 | 2.13 | + | 2.12E−07 |
Cytokine receptor binding | 218 | 15 | 2.63 | + | 2.12E−04 |
Receptor binding | 1030 | 33 | 12.41 | + | 8.36E−04 |
G-protein coupled receptor activity | 1445 | 3 | 17.42 | – | 4.06E−02 |
Cellular component | |||||
Cytoplasm | 7080 | 118 | 85.33 | + | 1.70E−02 |