Skip to main content

Table 3 Enrichment results for gene ontology (GO) analysis of differentially-methylated regions between selection lines across and within sexes

From: Epigenetics and early domestication: differences in hypothalamic DNA methylation between red junglefowl divergently selected for high or low fear of humans

GO ID

GO term

Across sexes

 GO:0005261

Cation channel activity

 GO:0003723

RNA binding

 GO:0003924

GTPase activity

 GO:0005759

Mitochondrial matrix

 GO:0006412

Translation

 GO:0006816

Calcium ion transport

 GO:0042254

Ribosome biogenesis

 GO:0042391

Regulation of membrane potential

Female

 GO:0044456

Synapse part

 GO:0043197

Dendric spine

 GO:0098878

Neurotransmitter complex

 GO:0022803

Passive transmembrane transporter activity

 GO: 0016597

Amino acid binding

 GO:0008066

Glutamate receptor activity

Male

 GO:1902710

GABA receptor complex

 GO:0045211

Postsynaptic membrane

 GO:0005657

Replication fork

 GO:0034776

Response to histamine

 GO:0006312

Mitotic recombination

 GO:0004520

Endodeoxyribonuclease activity

 GO:0005254

Chloride channel activity

 GO:0008094

DNA-dependent ATPase activity

  1. Annotations for differentially-methylated windows were used to search for enrichment of terms in the groups, both for overall effects of selection objective and sex-specific changes