Harnessing longitudinal information to identify genetic variation in tolerance of pigs to Porcine Reproductive and Respiratory Syndrome virus infection

Table 3 Genetic components of growth (ADG) and viral load (VL) at different stages of infection

Trait	ADG_early	ADG_mid	ADG_late	VL_early	VL_mid	VL_late
ADG_early	0.28 (0.07)	0.35 (0.03)	0.23 (0.03)	0.03 (0.03)	− 0.06 (0.03)	− 0.10 (0.03)
ADG_mid	0.70 (0.14)	0.22 (0.06)	0.36 (0.03)	0.03 (0.03)	− 0.08 (0.03)	− 0.13 (0.03)
ADG_late	0.77 (0.20)	0.84 (0.15)	0.16 (0.08)	− 0.05 (0.03)	− 0.20 (0.03)	− 0.19 (0.03)
VL_early	0.06 (0.23)	0.73 (0.24)	− 0.02 (0.27)	0.17 (0.10)	0.49 (0.03)	− 0.28 (0.03)
VL_mid	− 0.09 (0.18)	0.23 (0.20)	− 0.44 (0.20)	0.82 (0.08)	0.31 (0.12)	0.52 (0.02)
VL_late	− 0.41 (0.23)	− 0.36 (0.22)	− 0.74 (0.21)	0.09 (0.26)	0.75 (0.15)	0.21 (0.09)

Estimates of heritability of growth (ADG) and viral load (VL) are shown at early-, mid- and late-stages of infection (on the diagonal), and of genetic and phenotypic correlations between the traits (lower and upper off-diagonals, respectively). Phenotypic variance was calculated by summing animal, litter and pen within-trial variance components. Heritability was calculated by dividing the animal variance component by the phenotypic variance. Standard errors are in parentheses. Variance component estimates for the non-genetic random effects (from the corresponding univariate models) are in Additional file 1: Table S2

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