Harnessing longitudinal information to identify genetic variation in tolerance of pigs to Porcine Reproductive and Respiratory Syndrome virus infection

Table 4 Estimates of genetic variance components for ADG (g/d) regressed on VL

VL	ADG	Level-only model		Level-slope model				Model fit
VL	ADG	Level	Residual	Level	Covariance	Slope	Residual	P value
Mid	Mid	3.47 (1.56)	11.10 (0.61)	3.39 (1.56)	~0 (~ 0)	3.40E−03 (6.24E−03)	11.00 (0.62)	0.74
Mid	Late	2.33 (1.24)	11.9 (0.67)	2.52 (1.30)	− 6.90E−02 (9.61E−02)	1.64E−02 (1.02E−02)	11.60 (0.67)	0.02
Late	Late	1.96 (1.15)	12.00 (0.68)	1.97 (1.15)	~0 (~ 0)	~0 (~ 0)	12.00 (0.68)	1.00

ADG at mid- and late-stage of infection is regressed on VL at mid- and late-stage of infection. The last column denotes the p-value of the LRT used to test whether the level-slope model significantly improves the model fit over the level model. For definition of stages of infection, see text. Standard errors are in brackets. Estimates under 1E−07 have been reported as close to 0 (~ 0)

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