Fig. 7
From: Removal of alleles by genome editing (RAGE) against deleterious load
Effect of prioritizing variants with intermediate allele frequency, and in order of their deviation from expected homozygosity. Average fitness over ten generations of future breeding with 10,000 recessive deleterious variants, editing 1, 5, or 20 variants per sire. The discovery rate was 0.75. The lines show averages across 50 replicates