Table 3 Details of the most strongly associated SNPs (with a p value < 10−6) in each QTL region with antibody response to O. osteratgi
BTA | SNP name | Pos (bp) | p value | Gene | Favourable allele (freq) | Effecta | Annotation | Start of QTL | End of QTL | Other genes in the QTL region |
|---|---|---|---|---|---|---|---|---|---|---|
23 | rs455561091 | 33,302,807 | 3.61 × 10−7 | – | A (0.004) | 0.13 | Intergenic | 33,029,305 | 34,481,525 | GPLD1, MRS2, DCDC2, NRSN1, PRP4, PRP8, PRP6 |
21 | rs475710014 | 65,072,681 | 4.26 × 10−7 | – | A (0.054) | 0.03 | Intergenic | 65,072,681 | 65,072,681 | – |
14 | rs523857350 | 35,375,134 | 4.62 × 10−7 | – | A (0.005) | 0.11 | Intergenic | 35,375,134 | 35,740,556 | SULF1, ENSBTAG00000037399, SLCO5A1 |
4 | rs29026148 | 62,981,078 | 4.85 × 10−7 | – | A (0.650) | 0.02 | Intergenic | 62,981,078 | 62,993,200 | – |
19 | – | 7,584,712 | 5.43 × 10−7 | – | A (0.198) | 0.02 | Intergenic | 7,584,712 | 7,584,712 | – |
14 | rs439873982 | 7,893,299 | 7.67 × 10−7 | – | T (0.008) | 0.08 | Intergenic | 7,866,148 | 7,899,389 | – |
3 | – | 1,746,600 | 7.74 × 10−7 | GPA33 | T (0.004) | 0.12 | Intron | 945,572 | 6,388,604 | MPZL1, RCSD1, CREG1, CD247, POU2F1, DUSP27, MAEL, ILDR2, TADA1, POGK, ENSBTAG00000022504, ENSBTAG00000022954, FAM78B, UCK2, TMCO1, ALDH9A1, MGST3, LRRC52, RXRG, LMX1A, PBX1, ENSBTAG00000045987, ENSBTAG00000034449, NUF2, RGS5, RGS4 |
12 | rs379990763 | 9,621,581 | 8.25 × 10−7 | – | A (0.010) | 0.08 | Intergenic | 9,402,063 | 9,801,565 | – |
13 | rs209722101 | 70,057,265 | 9.50 × 10−7 | – | G (0.002) | 0.15 | Intergenic | 70,057,265 | 70,057,265 | – |