Management of lethal recessive alleles in beef cattle through the use of mate selection software

Table 6 Average sire index value ($MB) and genetic load scores (GLS) for different percentages of herd genotyped in three scenarios^a given two selection strategies^b

Scenario^a	Strategy^b		Weightings against selection strategies
Scenario^a	Strategy^b		0	0.001	0.01	0.1	1	10	100
A	1	$MB	141.03	141.03	141.03	140.98	140.61	141.03	141.03
		GLS	0.049	0.027	0.027	0.024	0.005	0	0
	2	$MB	141.03	141.03	141.03	141.03	141.03	141.03	141.03
		GLS	0.049	0.049	0.049	0.049	0.049	0.049	0.049
B	1	$MB	141.03	141.03	140.97	140.75	130.57	86.74	86.50
		GLS	0.287	0.287	0.281	0.265	0.157	0	0
	2	$MB	141.03	141.03	141.03	141.03	132.21	118.97	115.34
		GLS	0.287	0.284	0.284	0.259	0.177	0.131	0.113
C	1	$MB	141.03	141.03	141.03	140.80	133.75	84.90	84.90
		GLS	0.333	0.333	0.332	0.298	0.167	0.012	0.012
	2	$MB	141.03	141.03	140.93	138.81	131.60	116.11	110.06
		GLS	0.333	0.333	0.333	0.257	0.163	0.100	0.080

In italic characters = the profit maximizing weighting for a given scenario and breeding strategy
^aScenario A (7 loci with high-frequency LOF alleles), scenario B (76 loci with low-frequency LOF alleles), and scenario C (50 with high- and low-frequency loci)
^bSelection against carrier parents (strategy 1) and selection and mate allocation to avoid homozygous offspring (strategy 2)

ISSN: 1297-9686