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Fig. 4 | Genetics Selection Evolution

Fig. 4

From: Comparative genome analyses reveal the unique genetic composition and selection signals underlying the phenotypic characteristics of three Chinese domestic goat breeds

Fig. 4

Characterization of two selection signals encompassing the genes related to hair growth in TC. a Log2(θπ ratios), FST, and Tajima’s D values in 10-kb outlier windows overlapping with the FGF5 gene. b Representative Sanger sequence traces of two alleles at the c.-253G > A SNP site in the 5′-UTR of FGF5. c The allele frequency at the c.-253G > A SNP site in the 5′-UTR of FGF5 in five domestic goat breeds (CB, JT, TC, MD, and MN) and Bezoar ibexes. d The predicted premature amino acid sequence caused by the mutant allele ‘A’ at the c.-253G > A SNP site in the 5′-UTR of FGF5. e Log2(θπ ratios), FST, and Tajima’s D values in 10-kb outlier windows encompassing DSG2, DSG3, and DSG4. f Pairwise LD between the three missense SNPs (chr24: 25,985,493, 25,985,494, and 25,985,569) and other SNPs in the DSG3 gene in TC. Squares in pink or red indicate significant LD between SNP pairs (bright red indicates pairwise D′ = 1). g The haplotype frequencies composed of the seven SNPs showing perfect LD in the five domestic goat breeds (CB, JT, TC, MD, and MN) and Bezoar ibexes

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