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Table 5 Values for plasma homocysteine concentration at 48 and 70 weeks of age, production data, radiographic density, mechanical and physicochemical bone properties measured at 70 weeks of age between CBS genotype Ost106225194/Ost112522587 (AA/AA vs. GG/GG) in Population 5

From: An eQTL in the cystathionine beta synthase gene is linked to osteoporosis in laying hens

 

Trait

AA/AA mean

se

GG/GG mean

se

P value

df

Radiographic, mechanical, metabolite and production data

 Body weight

Body weight (g)

1638

24

1603

24

0.291

1,64

 Egg traits

Egg number

282.3

1.8

276.0

2.3

0.574

1,64

Egg breaking strength (48 wk of age)

40.1

0.9

40.4

1.3

0.508

1,61

 Plasma homocysteine

Homocysteine 48 wk of age (µM/L)

18.64

0.55

16.68

0.64

0.024

1,52

Homocysteine 70 wk of age (µM/L)

19.13

0.46

17.18

0.63

0.016

1,64

Detailed morphometry and physicochemical analysis

 Bone type

  Whole tibia

Breaking strength (N)

228.1

6.6

228.2

9.0

0.998

1,36

  Whole tibia

Stiffness (Nm)

316,939

8456

322,940

9526

0.64

1,36

  Whole tibia

Density (mm Al equiv/mm3)

1.60

0.01

1.61

0.01

0.412

1,36

% cortical bone

56.84

2.33

50.84

2.30

0.075

1,36

 Tibia cortical

  Tibia cortical

Density (mmAl equiv/mm3)

0.018

0.001

0.022

0.001

0.024

1,36

  Tibia cortical

MinCO3 1415

0.209

0.003

0.170

0.003

< 0.001

1,36

  Tibia cortical

CI 1030/1020

0.584

0.004

0.633

0.007

< 0.001

1,36

  Tibia cortical

PO4/Amide I

3.97

0.11

6.40

0.12

< 0.001

1,36

  Tibia cortical

LNK 1660/1690

2.54

0.12

4.17

0.19

< 0.001

1,36

  Tibia cortical

AngSpread 002

54.9

0.91

49.4

0.66

0.004

1,35

  Tibia cortical

FWHM002

0.45

0.01

0.46

0.017

0.842

1,36

  Tibia medullary

Density (mmAl equiv/mm3)

0.025

0.003

0.024

0.002

0.743

1,36

  Tibia medullary

MinCO3 1415

0.18

0.03

0.16

0.02

0.576

1,36

  Tibia medullary

CI 1030/1020

0.77

0.022

0.73

0.02

0.149

1,36

  Tibia medullary

PO4/Amide I

1.17

0.09

1.25

0.10

0.585

1,36

  Tibia medullary

LNK 1660/1690

3.20

0.09

3.20

0.07

0.998

1,36

  Tibia medullary

FWHM002

0.58

0.03

0.56

0.02

0.425

1,35