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Table 1 Summary of the sheep obtained with the targeted point mutations via ABEmax

From: Highly efficient generation of sheep with a defined FecBB mutation via adenine base editing

Donor sheep 10
Collected embryos 96
ABEmax-sgRNA
 Injected embryos 96
 Transferred embryos 95
Recipient sheep 18
Pregnant recipients 6
Newborns 8
 Expected defined substitution 6
 Un-defined substitution 2
  1. ABEmax: the latest version of adenine base editors; sgRNA: single guide RNA