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Fig. 1 | Genetics Selection Evolution

Fig. 1

From: pCADD: SNV prioritisation in Sus scrofa

Fig. 1

a Fixed alleles that differ between the investigated pig population and an inferred ancestor sequence are used as proxy benign/neutral SNVs. b First step of the simulation: differences between evolutionary differently distant ancestor sequences are identified and substitution rates are derived. c Simulation, second step: the derived substitution rates are used to simulate de novo variants that have not experienced any selection and thus are not depleted in deleterious variants

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Genetics Selection Evolution

ISSN: 1297-9686