Table 4 Expression quantitative trait loci (eQTL, which include gene expression QTL (geQTL), exon expression QTL (eeQTL), and splicing QTL (sQTL)) enriched in genome-wide association study (GWAS) hit regions linked with fatty acid profiles [29]
From: Expression quantitative trait loci in sheep liver and muscle contribute to variations in meat traits
Fatty acid | Liver geQTL | Liver eeQTL | Liver sQTL | Muscle geQTL | Muscle eeQTL | Muscle sQTL |
|---|---|---|---|---|---|---|
Saturated fatty acid (SFA) | ||||||
 Myristic acid (C14:0) | 612 (1.2e−33) | 229 (0.15) | 707 (9e−51) | 1255 (0e + 00) | 1176 (0.00) | 233 (0.15) |
 Palmitic acid (C16:0) | 406 (2.6e−26) | 0 (1.00) | 0 (1.00) | 0 (1.00) | 0 (1.00) | 340 (1.2e−48) |
 Stearic acid (C18:0) | 296 (6.7e−03) | 5 (1.00) | 570 (5.4e−59) | 997 (0.00) | 43 (1.00) | 150 (0.6) |
 Total SFA | 617 (5.8e−08) | 3 (1.00) | 1978 (0.00) | 55 (1.00) | 43 (1.00) | 5 (1.00) |
Monounsaturated fatty acids (MUFA) | ||||||
 Palmitoleic acid (C16:1) | 764 (1.7e−13) | 9 (1.00) | 2031 (0.00) | 947 (8.8e−178) | 61 (1.00) | 147 (1.00) |
 Oleic acid (C18:1) | 94 (1.00) | 5 (1.00) | 226 (1.00) | 61 (1.00) | 36 (1.00) | 56 (1.00) |
 Total MUFA | 221 (1.00) | 3 (1.00) | 1505 (7.8e−152) | 32 (1.00) | 36 (1.00) | 0 (1.00) |
Polyunsaturated fatty acids (PUFA) | ||||||
 Linoleic acid (C18:2, ω6) | 396 (1.1e−51) | 0 (1.00) | 0 (1.00) | 0 (1.00) | 0 (1.00) | 0 (1.00) |
 alpha-Linolenic acid (C18:3, ω3) | 1172 (2.1e−116) | 696 (9.6e−71) | 292 (1.00) | 818 (4.6e−128) | 329 (2.1e−18) | 183 (1.00) |
 Conjugated linoleic acid (CLA, c9t11) | 277 (2e−17) | 96 (0.45) | 142 (0.99) | 88 (0.58) | 6 (1.00) | 201 (3e−21) |
 Total ω3 | 0 (1.00) | 197 (1.5e−03) | 127 (1.00) | 0 (1.00) | 0 (1.00) | 65 (1.00) |
 Total ω6 | 396 (1.6e−37) | 0 (1.00) | 0 (1.00) | 0 (1.00) | 6 (1.00) | 0 (1.00) |
 Total PUFA | 396 (6.7e−10) | 0 (1.00) | 0 (1.00) | 1 (1.00) | 6 (1.00) | 0 (1.00) |
ω6/ω3 and PUFA/SFA ratios | ||||||
 ω6/ω3 | 418 (1.00) | 13 (1.00) | 1481 (4.4e−128) | 208 (1.00) | 36 (1.00) | 0 (1.00) |
 PUFA/SFA | 396 (3.6e−154) | 0 (1.00) | 0 (1.00) | 0 (1.00) | 0 (1.00) | 0 (1.00) |
 Total | 6849 |  |  | 4610 |  |  |