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Table 2 List of Lacaune deficient homozygous haplotypes

From: Identification of homozygous haplotypes carrying putative recessive lethal mutations that compromise fertility traits in French Lacaune dairy sheep

Haplotype

OAR

Number of markersa

Positionb (Mb)

Carrier frequencyc (%)

Number of homozygotes

Expd

Obse

Deficit (%)

Poisson P-value

LDHH1

4

46/42

43.4–46.3

6.7

21

0

100

7.6 × 10−10

LDHH2

13

28/26

44.8–46.8

6.2

17

0

100

4.1 × 10−8

LDHH3

3

48/39

32.0–34.9

4.3

10

0

100

7.0 × 10−5

LDHH4

3

24/19

132.4–133.9

3.8

10

0

100

5.5 × 10−5

LDHH5

3

29/23

131.1–132.7

3.7

9

0

100

1.9 × 10−4

LDHH6

3

27/21

136.2–137.4

12.1

72

3

96

3.5 × 10−27

LDHH7

17

29/27

0.0–1.6

4.7

12

1

92

9.9 × 10−5

LDHH8

18

23/20

25.7–27.5

5.5

14

2

86

9.4 × 10−5

LDHH9

18

37/33

31.3–33.5

4.4

13

2

85

2.2 × 10−4

LDHH10

18

26/23

33.0–34.6

5.7

17

3

82

4.1 × 10−5

LDHH11

3

28/28

128.9–131.1

7.2

19

4

79

3.8 × 10−5

  1. aNumber of LDHH markers refers to ovine genome reference assembly Oar_v2.0/Oar_v3.1 and listed in Additional file 2: Table S3
  2. bPosition on ovine genome assembly Oar_v3.1
  3. cFrequency of carriers in the entire genotyping population (n = 19,102)
  4. dExpected
  5. eObserved