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Table 1 PrP-specific monoclonal antibodies used to detect full-length PrPC, C1, and C2

From: Caprine PRNP polymorphisms N146S and Q222K are associated with proteolytic cleavage of PrPC

Antibody

Epitopea

Isotype

Referencesb

BC6

144FGNDYEDRYYR154

IgG1

[26]

FH10

202TETDIKIME210

IgG2a

[26]

F89/160.1.5

142IHFG145

IgG1

[28]

F99/97.6.1

220QYQRES224

IgG1

[27]

  1. aAmino acids in bold font may be altered due to single nucleotide polymorphisms known to occur in caprine PRNP [29]. Underlined amino acids are the focus of the current study
  2. bFirst description of prion protein-specific antibody
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Genetics Selection Evolution

ISSN: 1297-9686