Fig. 4
From: A major QTL at the LHCGR/FSHR locus for multiple birth in Holstein cattle
Graphical representation of the associated QTL region and linkage disequilibrium (LD) analysis results for the mbm trait. a Screenshot of the region on bovine chromosome 11 between 30.5 and 32.5 Mb from the NCBI Genome Browser including the localization of the genes in the region. b Screenshot of the region on bovine chromosome 11 between 30.95 and 31.5 Mb from the NCBI Genome Browser including the localization of the candidate genes LHCGR and FSHR. The purple bar shows the localization of the top-associated haplotype. The red star represents the variant with the highest LD score. c The resulting haplotypes from the haplotype regression analysis are shown with their localization. The 880-kb region with the top-associated haplotypes from 30.47 to 31.35 Mb used for subsequent fine-mapping is highlighted in red. d Heatmap showing the LD in the region between 30.47 and 31.35 Mb on bovine chromosome 11 highlighting the haplotype that was added as an additional variant. The localization and chromosomal orientation of LHCGR and FSHR are displayed (black arrows). e The variants in r2 ≥ 0.6 with the top-associated haplotype are highlighted and shown with their position on bovine chromosome 11