Table 5 Wright’s fixation statistic (FST) by predicted consequence type and prevalence level
From: Rare and population-specific functional variation across pig lines
Consequence type | FST by prevalence level | ||||||||
|---|---|---|---|---|---|---|---|---|---|
2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | Total | |
Loss-of-function | 0.003 | 0.022 | 0.047 | 0.066 | 0.094 | 0.114 | 0.145 | 0.171 | 0.071 |
Frameshift indel | 0.010 | 0.042 | 0.065 | 0.081 | 0.088 | 0.120 | 0.146 | 0.148 | 0.114 |
In-frame indel | 0.011 | 0.035 | 0.051 | 0.070 | 0.087 | 0.105 | 0.115 | 0.130 | 0.077 |
Deleterious missense | 0.005 | 0.029 | 0.055 | 0.073 | 0.087 | 0.110 | 0.131 | 0.160 | 0.068 |
Tolerated missense | 0.009 | 0.036 | 0.061 | 0.084 | 0.107 | 0.127 | 0.158 | 0.184 | 0.108 |
Synonymous | 0.013 | 0.040 | 0.062 | 0.090 | 0.110 | 0.130 | 0.158 | 0.194 | 0.117 |
Promoter + UTR | 0.009 | 0.036 | 0.060 | 0.086 | 0.108 | 0.131 | 0.158 | 0.190 | 0.110 |
Intronic | 0.009 | 0.037 | 0.063 | 0.089 | 0.111 | 0.136 | 0.164 | 0.195 | 0.118 |
Intergenic | 0.009 | 0.036 | 0.066 | 0.091 | 0.112 | 0.139 | 0.167 | 0.193 | 0.121 |