Table 2 Possible two-locus genotype counts when one of the four possible haplotypes (AB, Ab, aB, ab) is missing, as determined by a zero genotype count at one of the four corners of the genotype count table
From: Failing the four-gamete test enables exact phasing: the Corners’ Algorithm
Corner I, Missing haplotype AB, double heterozygotes are phased Ab/aB | |||
|---|---|---|---|
BB | Bb | bb | |
AA | 0 | 0 | nAAbb |
Aa | 0 | nAaBb | nAabb |
aa | naaBB | naaBb | naabb |
Corner II, Missing haplotype Ab, double heterozygotes are phased AB/ab | |||
|---|---|---|---|
BB | Bb | bb | |
AA | nAABB | 0 | 0 |
Aa | nAaBB | nAaBb | 0 |
aa | naaBB | naaBb | naabb |
Corner III, Missing haplotype aB, double heterozygotes are phased AB/ab | |||
|---|---|---|---|
BB | Bb | bb | |
AA | nAABB | nAABb | nAAbb |
Aa | 0 | nAaBb | nAabb |
aa | 0 | 0 | naabb |
Corner IV, Missing haplotype ab, double heterozygotes are phased Ab/aB | |||
|---|---|---|---|
BB | Bb | bb | |
AA | nAABB | nAABb | nAAbb |
Aa | nAaBB | nAaBb | 0 |
aa | naaBB | 0 | 0 |