Single-step genome-wide association analyses of claw horn lesions in Holstein cattle using linear and threshold models

Table 4 Estimates of additive genetic variance (Va), permanent environmental variance (Vpe), residual variance (Ve), and heritability (h²) for lesion susceptibility and severity of sole haemorrhage (SH), sole ulcers (SU), and white line disease (WL)

Trait	Model	Lesion	Va	Vpe	Ve	h²
Lesion susceptibility^a (binary trait)	Threshold model	SH	0.42 (0.14)	–	1.01 (0.04)	0.29 (0.07)
		SU	0.56 (0.20)	–	1.01 (0.05)	0.35 (0.08)
		WL	0.12 (0.08)	–	1.01 (0.04)	0.10 (0.06)
Lesion severity^b (continuous trait)	Linear model	SH	0.012 (0.002)	9.8E−3 (0.002)	0.077 (0.001)	0.12 (0.02)
		SU	0.001 (2E−4)	0.003 (3E−4)	0.008 (1E−4)	0.07 (0.02)
		WL	0.003 (8E−4)	0.003 (0.001)	0.069 (0.001)	0.04 (0.01)

Posterior standard deviations of estimates (for lesion susceptibility traits) or standard errors of estimates (for lesion severity traits) are in brackets
^aLesion susceptibility classified animals as either affected at any time point (case, 1) or unaffected throughout the period of study (control, 0); estimates are expressed on the liability scale
^bThe lesion severity of an individual was calculated as the average lesion score of all assessed feet

ISSN: 1297-9686