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Table 2 Genomic regions associated with coefficients of reaction norm models for post-weaning weight gain in Nellore cattle, and annotated genes within those regions

From: Unraveling genetic sensitivity of beef cattle to environmental variation under tropical conditions

Region %Vara Chrb Window startb (bp) Window endb (bp) Gene stable IDc Gene symbolc
b0 b1 b0s b1s1 b1s2
1    0.55 0.55   1 84,867,382 85,267,382 – –
2      0.58 3 35,940,081 36,344,427 ENSBTAG00000014530 NTNG1
3      0.78 3 96,120,576 96,520,576 ENSBTAG00000014482 FAF1
ENSBTAG00000045402 RF00322
ENSBTAG00000010414 DMRTA2
4     0.55   3 114,849,177 115,249,177 ENSBTAG00000013869 SH3BP4
5 0.56   1.52 1.61   4 8,329,351 8,741,255 ENSBTAG00000002107 FZD1
ENSBTAG00000027319  
6 1.00 0.88 1.25 1.14   5 84,442,697 84,878,158 ENSBTAG00000039906  
ENSBTAG00000046108  
ENSBTAG00000000749 LMNTD1
7      0.74 7 22,728,136 23,164,748 ENSBTAG00000009034 AP3D1
ENSBTAG00000025448 IZUMO4
ENSBTAG00000014526 MOB3A
ENSBTAG00000018049 MKNK2
ENSBTAG00000025445  
ENSBTAG00000008609 SEPT8
ENSBTAG00000031246 CCNI2
ENSBTAG00000025477 KIF3A
ENSBTAG00000015957 IL4
ENSBTAG00000015953 IL13
ENSBTAG00000011252 RAD50
8    0.76 0.75   7 95,572,442 95,972,442 – –
9      0.82 8 107,325,318 107,747,332 ENSBTAG00000004010 PAPPA
ENSBTAG00000047511  
ENSBTAG00000025667  
ENSBTAG00000017155 TRIM32
10      0.53 9 58,226,166 58,643,182 – –
11      0.50 10 7,290,264 7,690,264 ENSBTAG00000017507 SV2C
ENSBTAG00000000897 IQGAP2
12 0.79 0.63     11 22,788,685 23,203,999 ENSBTAG00000013861 SLC8A1
ENSBTAG00000037153 RF00001
13 0.60 0.63 0.68 0.55   11 56,219,017 56,652,372 ENSBTAG00000007135 REG3G
ENSBTAG00000011314 REG3A
14 0.56 0.64 0.77 0.74   14 19,482,365 19,901,806 ENSBTAG00000044730 RF00026
ENSBTAG00000019892 HAS2
15      0.50 14 72,964,805 73,364,805 – –
16      0.83 16 64,552,728 64,958,425 ENSBTAG00000046243 ZNF648
ENSBTAG00000027426  
ENSBTAG00000013631 GLUL
17   0.50     17 7,729,955 8,129,955 ENSBTAG00000008098 DCLK2
18    0.51    17 11,993,902 12,393,902 ENSBTAG00000034522 SLC10A7
ENSBTAG00000048020  
ENSBTAG00000014060 LSM6
19 0.54      18 59,112,039 59,512,039 ENSBTAG00000045571  
ENSBTAG00000037440  
ENSBTAG00000047712  
ENSBTAG00000030454  
ENSBTAG00000011052  
20 0.84 0.71     20 65,401,804 65,809,687 ENSBTAG00000009401 MTRR
ENSBTAG00000009400
ENSBTAG00000019210 		FASTKD3
ADCY2
21      0.63 27 11,730,389 12,130,389 ENSBTAG00000047427 RF00100
22      0.52 27 32,310,351 32,710,351 ENSBTAG00000033381  
ENSBTAG00000013943 ZNF703
23      0.62 29 12,876,785 13,278,418 ENSBTAG00000033731 PRCP
ENSBTAG00000006812 FAM181B
ENSBTAG00000044832  
  1. aPercentage of genetic variance (%Var) explained by the leading segment (within region) of five adjacent SNPs, for each coefficient. b0: intercept of a heteroscedastic linear reaction norm model (RNM_hete); b1: slope of RNM_hete; b0s: intercept of a heteroscedastic spline linear–linear reaction norm model (RNM_l-l); b1s1: slope of segment 1 of RNM_l-l; b1s2: slope of segment 2 of RNM_l-l. Only  %Var ≥ 0.5% are presented
  2. bChromosome (Chr) and bp position (bpp) according to the UMD3.1 assembly
  3. cRetrieved from the BioMart Ensembl genes 93 database; genes with human orthologs, used for enrichment analyses, are presented in italics
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Genetics Selection Evolution

ISSN: 1297-9686